#Note/Permanent #Neuroscience/Dopamine #Nutrition/Caffeine Caffeine, a widely consumed stimulant, interacts with the dopamine system in a unique manner. Unlike other stimuli that cause a [[Dopamine's Influence on Behavior and Addiction|sharp increase and subsequent drop]] in dopamine levels, caffeine works by upregulating certain dopamine receptors[^1]. This upregulation leads to a more prolonged and stable enhancement of dopamine's effects, avoiding the drastic crash typically associated with other dopamine-boosting activities. [^1]: https://www.nature.com/articles/tp201546